Brief historical perspective of chemotherapy. Fundamental principles of rational chemotherapy – selective toxicity principle. Classification of antimicrobial agents with special reference to the mechanism of action and chemical structures.Drugs inhibiting cell-wall synthesis - beta-lactam antibiotics. Inhibitors of protein synthesis - aminoglycosides, macrolides, tetracyclines.Drugs which interfere with cell membrane integrity.Inhibitors of RNA and DNA Synthesis – rifampicin and quinolones. Miscellaneous antimicrobials, e.g., sulphonamides, trimethoprim, fusidic acid, clindamycin, lincomycin, chloramphenicol. AntifungalAgents. AntiviralAgents. Interferon and Interferon Inducers.Chemotherapy of some parasitic infections. Development of resistance to antibiotics by microorganisms: plasmid-mediated and biochemical basis. Control of emergence of resistance.
They are to be taught topics including: concept of management (different views with a brief mention of schools of thought), management resources and its relevance; business environment; Elements of the management process/functions of management: planning, organizing, controlling, staffing, leadership, delegation of authority, motivation, communication etc; key result areas in management should be discussed briefly: human resources management, financial management, marketing management; drug supply management: procurement methods and quantification techniques; inventory control methods. Health policy and planning, among others.
Health conditions where herbalists are frequently consulted: Diseases of the CVS, GIT, CNS, endocrine and Reproductive systems. Names of medicinal plants, chemical constituents, and biological activities. Possible reasons for synergy, antagonisms and contraindication and drug-herb interactions.
This course is a review of basic pharmacology. The areas to be covered will include the transfer of drug across biological membranes; absorption, distribution, biotransformation and elimination of drugs; routes of administration; mechanisms of drug action including the theories of drug-receptors interaction, structure-activity relationships, dose-response relationships; and review of the anatomy and physiology of the autonomic and central nervous systems and the drugs affecting the systems.
Principles of radiation hygiene applied in radiopharmacy : handling, labeling, dispensing and storage of radiopharmaceuticals; radiation hazards and precautions against such hazards; chemical protection against radiation eg thiols and thiol derivatives cysteine and cysteamine; organic nitriles eg fluoroacetate ion; chelating agents oxine and EDTA; physiologically and Pharmacologically active substances serotonin, catecholamines, chlorpromazine and hydroxylated compounds such as propylene glycol.
Inflammation and repair; Pathophysiology of diseases of the following systems: gastrointestinal system, renal system, respiratory system, cardiovascular system; central nervous system diseases and neoplastic diseases.
Hemodynamic diseases; musculoskeletal diseases; infectious diseases; deficiency diseases; endocrine diseases; hepatic diseases; diseases of the ear, eyes, and skin. The normal cell and the adopted cell; cell injury and cell death.
Evaluate the symptomatic complaints of a patient typically encountered in a community pharmacy setting. The objective of the course is to equip pharmacists with the competency to manage self-care in the community. Course contents include: concepts of self-care and self-medication; Self-care practices including hand washing, lifestyle management; Factors driving self-care. Responsible self-medication with OTC drugs; Responding to symptoms/ counter prescribing & referrals. Role of pharmacists in self-medication; First Aid principles and common conditions requiring first aid
Case studies and WHO/other standard indicators/prescribing guidelines are employed as approaches to developing the ideas of rational drug therapy, monitoring drug therapy and interactions.
Areas to be covered will include, fluid and electrolyte balance, pulmonary systems, gastroenterology, rheumatology, endocrinology, medical emergencies and critical care therapeutics including treatment of poisoning and adverse drug reactions.
The role of drug information centers in serving as an audience of primarily health professionals but in some settings meet to consumer needs. Stress the general areas of responsibility, namely, service, education and research. Students will be taught how to acquire and critically appraise the scientific evidence for its validity and usefulness. The methods used to access, retrieve, evaluate, store and manage the literature and database worldwide for current and emerging research/clinical findings on drugs including indications, contraindications, reactions and interactions should be highlighted. Emphasis also on specific functions such as answering questions, supporting the Pharmacy and Therapeutics Committee, and preparing newsletters in paper and/or e-format. Educational responsibilities which often include teaching pharmacy students drug information skills should be mentioned.
This course will cover an overview of epidemiological methods (types of epidemiological studies, sampling techniques, sample size and power); epidemiology of communicable and non-communicable diseases. It will also cover Literature search, data gathering modalities, questionnaire design, approaches to data analysis, operational research and experimental design and report writing. Other areas include Principles and concept of Primary Health Care (PHC); Drug use and management in PHC (commonly used drugs, drug selection and distribution/essential drug list concept and drug information/education in primary health care; and Traditional Medicines in PHC. with emphasis on health technology and available resources, community participation, etc;
Definition of terminology and symbols used in pharmacokinetics. Fate of a drug after administration; Physical significance of drug concentration in the blood; Biological factors in drug absorption; Physicochemical factors affecting drug absorption; Dosage form consideration in gastrointestinal absorption; Drug-drug and drug-food interactions, bioavailability and bioequivalence with emphasis on product registration with regulatory bodies.
Case studies and WHO/other standard indicators/prescribing guidelines are employed as approaches to developing the ideas of rational drug therapy, monitoring drug therapy and drug interaction. Areas to be covered will include cardiovascular systems, nephrology, psychiatry/neurology, hematology/ oncology, infectious diseases (including HIV/AIDS and STDs), common eye and ear disorders, paediatric and geriatric drug therapeutics, drug therapy in pregnancy and clinical toxicology.